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KMID : 0363220080460060788
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Korean Journal of Dermatology
2008 Volume.46 No. 6 p.788 ~ p.791
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Acquired Reactive Perforating Collagenosis in a Chronic HCV Hepatitis Patient Who was Treated with Interferon Alpha
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Choi Yeon-Jin
Park Mi-Youn
Shin Mi-Seon
Ahn Ji-Young
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Abstract
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Reactive Perforating Collagenosis (RPC) is a kind of perforating dermatosis, which shows transepidermal elimination
of altered collagens. Acquired form is developed in an adult without family history, is favorably developed in scratched region due to pruritic sense. Acquired RPC has been reported to be associated with various systemic disorders, such as diabetes mellitus, liver disease, chronic renal failure, lymphoma, AIDS, hypothyroidism, hyperparathyroidism, and neurodermatitis, accompanied by itching & scratching. We report a case of acquired RPC in a patient with HCV hepatitis who was treated with interferon alpha. Skin lesions showed multiple erythematous centrally umbilicated, crusted papules of variable sizes on the extensor surfaces of both shins. (Korean J Dermatol 2008;46(6):788∼791)
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KEYWORD
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Acquired reactive perforating collagenosis, HCV, Interferon alpha
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